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Triterpenoid pyrazines and pyridines – synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
Eur. J. Med. Chem. 2022, 243 (N/A), 114777. DOI: 10.1016/j.ejmech.2022.114777
Pokorný, J.; Olejníková, D.; Frydrych, I.; Lišková, B.; Gurská, S.; Benická, S.; Šarek, J.; Kotulová, J.; Hajdúch, M.; Džubák, P.; Urban, M.
Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters
Eur. J. Med. Chem. 2021, 224 (n/a), 113706(1-18). DOI: 10.1016/j.ejmech.2021.113706
de Jong, F.; Pokorny, J.; Manshian, B.; Daelemans, B.; Vandaele, J.; Startek, J. B.; Soenen, S.; Van der Auweraer, M.; Dehaen, W.; Rocha, S.; Silveira-Dorta, G.
Development and Characterization of BODIPY-Derived Tracers for Fluorescent Labeling of the Endoplasmic Reticulum
Dyes and Pigments 2020, 176 (-), 108200. DOI: 10.1016/j.dyepig.2020.108200
Hodoň, J.; Borkova, L.; Pokorny, J.; Kazakova, A.; Urban, M.
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research
Eur. J. Med. Chem. 2019, 182 (N/A), Article Number: 111653 (1-25). DOI: 10.1016/j.ejmech.2019.111653
Pokorný, J.; Borková, L.; Urban, M.
Click Reactions in Chemistry of Triterpenes – Advances Towards Development of Potential Therapeutics
Current Med. Chem. 2018, 25 (5), 636-658. DOI: 10.2174/0929867324666171009122612
Pokorný, J.; Krajčovičová, S.; Hajdúch, M.; Holoubek, M.; Gurská, S.; Džubák, P.; Volná, T.; Popa, I.; Urban, M.
Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM
Future Med. Chem. 2018, 10 (5), 483-491. DOI: https://doi.org/10.4155/fmc-2017-0171
Pokorný, J.; Horka, V.; Šidová, V.; Urban, M.
Synthesis and characterization of new conjugates of betulin diacetate and bis(triphenysilyl) betulin with substituted triazoles
Monatsh. Chem. 2018, 149 (4), 839-845. DOI: 10.1007/s00706-017-2113-7
Šidová, V.; Zoufalý, P.; Pokorný, J.; Džubák, P.; Hajdúch, M.; Popa, I.; Urban, M
Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives
PLoS ONE 2017, 12 (2), e0171621. DOI: 10.1371/journal.pone.0171621